Bioengineering Seminar Series - Dr. Jason Szafron

Dr. Jason Szafron, Assistant Professor, Biomedical Engineering at Carnegie Melon University, will present "Computational biomechanics in vascular treatment planning for cardiopulmonary disease."

Abstract

Many forms of cardiopulmonary disease require interventions with a vascular component. The biomechanical environment prior to intervention can have implications for the success of a procedure, and the post-intervention hemodynamics can lead to long-term pulmonary remodeling that exacerbates the risk for future complications. In this talk, I will discuss our work using computational fluid dynamics to predict the success of mechanical thrombectomy in acute pulmonary embolism patients and the resulting biomechanical environment with lung transplant in pulmonary arterial hypertension. I will also outline our approach to using multiscale simulations of the pulmonary vasculature to predict changes in clinically relevant metrics of disease progression.