The sweet side of attention and compulsive behaviour: an immunometabolic nexus regulated by K+ channels

Speaker: Jeffrey Glennon, University College Dublin
Series: Zangwill Club

Attention problems, impulse control and compulsive behaviour are key behavioural elements common across both neurodevelopmental and neurodegenerative disorders. Building on large genetic data sets, we ascertained that dysregulated insulin signaling leading to inflammatory challenges may be a converging mechanism. This impacts both immunometabolic control and the proteome with K+ channels playing an important modulatory role. Within this presentation, I will expand on our current mechanistic understanding and highlight novel strategies in modulating compulsivity and attention.

Host: Prof Amy Milton

This talk may be recorded and uploaded to the Zangwill Club Youtube channel in due course.